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119 results found


Breast cancer

T-DM1 and Placebo Compared With T-DM1 AND Tucatinib in HER2-Positive Breast Cancer

This study focuses on patients who have human epidermal growth factor receptor 2 (HER2)-positive breast cancer and who have already received treatment with chemotherapy and anti-HER2 targeted therapies followed by surgery. The study will evaluate ...


Lung

Open vs. Thoracoscopic Management of Pulmonary Metastases in Patients With Osteosarcoma

The purpose of this study is to compare the effects of 2 surgery methods for people with bone cancer (osteosarcoma- OST) that has spread to the lung. The 2 types of surgeries are called open ...


Breast cancer

Ivermectin and Balstilimab in Metastatic Triple Negative Breast Cancer

The purpose of this study is to evaluate whether concurrent use of oral ivermectin and intravenous (IV) balstilimab is safe and effective in treating patients with triple negative breast cancer. Researchers want to know the ...


Colon, Pancreas, Stomach

CUE-102 in Recurrent / Metastatic Cancers

The purpose of this study is to evaluate the safety and effects of an investigational drug called CUE-102 in cancer patients. The study will include patients who have colorectal, gastric, pancreatic or ovarian cancer that ...


Melanoma

Adjuvant MK-7684A Versus Adjuvant Pembrolizumab in High-Risk Stage II-IV Melanoma

The purpose of this study is to evaluate an experimental drug called MK-7684A in adults and children who have had surgery to remove their melanoma. MK-7684A, a type of immunotherapy, is given as a combination ...