Find Clinical Trials | Cedars-Sinai

217 results found

Cervix, Esophagus, Kidney, Liver, Lung, Melanoma, Urinary Bladder

MT-8421 as Monotherapy and in Combination With Nivolumab

The purpose of this study is to evaluate the safety and efficacy of an investigational drug called MT-8421 alone and when given with another drug, nivolumab, in patients with advanced cancer. Researchers also want to ...

Colon, Liver, Other Female Genital

E7386 in Combination With Other Anticancer Drug(s) in Solid Tumors

The purpose of this study is to determine whether an experimental drug called E7386 in combination with another drug, lenvatinib, is safe and effective in people who have an advanced solid tumor, including colorectal, hepatocellular, ...

Hodgkin's Lymphoma, Leukemia, not otherwise specified, Leukemia, other, Lymphoid Leukemia ...

Post-Transplant Cyclophosphamide

The purpose of this study is to determine the best dose of an immune suppressive drug, cyclophosphamide, following standard stem cell transplant in older patients (at least 65 years old). Participants will undergo a stem ...

Anus, Bones and Joints, Brain and Nervous System, Breast, Cervix ...

Allogenic Blood-Derived Natural Killer Cells in Cancer Refractory to Conventional Therapy

The purpose of this study is to evaluate a blood-derived experimental therapy in patients who have refractory cancer that has failed conventional, standard-of-care therapy. Researchers will use natural killer (NK) cells to create the study ...

Lung

Harpoon Therapeutics, HPN328-4001, Ph 1/2, OL, advanced SCLC/tumors with expression of DLL3, HPN328

Primary Objectives -Assess safety and tolerability at increasing dose levels of HPN328 in successive cohorts of patients with solid tumors associated with expression of DLL3 -Estimate the maximum tolerated dose (MTD) or select the recommended Phase 2 ...